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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare providers to choose the appropriate test the first time. Patients benefit from faster diagnosis and more targeted treatment. Clinicians benefit from improved stewardship for antibiotics. Labs improve efficiency and cost savings. The BioFire Pneumonia Plus Panel (PN panel) analyzes native sputum (including mini-BAL), endotracheal lavage, and bronchoalveolar slurries (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials in one hour. Respiratory The burning of biomass, such as plants, wood and other organic materials, produces gaseous pollution and fine particles that adversely affect the respiratory system. Climate change can make it more difficult to reverse the negative effects of forest fires on human health. In the United States, wildfire smoke has been linked to respiratory diseases like asthma, COPD and lung cancer. This type of air pollution also increases the risk of developing cardiovascular disease, and is a major contributor to the burden on disease among the most vulnerable populations. In the COVID-19 epidemic, many communities were exposed to unhealthy levels of air pollution resulting from wildfires. However, the public health response to this environmental problem has been limited and largely focused on communication about the management of symptoms. This knowledge gap is alarming given the evidence that smoking cigarettes and other causes of air pollution can lead to health problems. Researchers are now evaluating the best ways to safeguard public health during future events of this type. NIH is a research institution that studies this critical public health issue through the BLUE CORAL and FIRE CORAL studies. For the first time the study is a prospective cohort study that will assess long-term outcomes from exposure to smoke from wildfires as well as other sources. FIRE CORAL is recruiting adult participants who have been hospitalized for COVID-19's index episode who have a fluency in English or Spanish and are not pregnant. The protocol for Fire Coral includes a series of in-person assessments that objectively measure pulmonary function testing lung imaging and functional assessment. Smoke and other particles can cause or worsen respiratory problems such as emphysema, COPD and pneumonia. Smoke exposure can have adverse effects on health. To minimize or avoid these negative effects, avoid outdoor activities and use the EPA “N95” mask. This mask is designed to capture small particles. Smoking can cause irritation to the throat, eyes and nose. To minimize symptoms the lungs need to be flushed by drinking plenty of fluids and taking medications that reduce inflammation, such as corticosteroids. Bloodstream Your bloodstream is on the front lines of fighting off germs that enter your body. Dendritic cells, which are special cells, function as a call center your fire department. They collect antigens from bacteria and release proteins to alert other white cells to fight. The white blood cell counts, differentials and band cells were increased during firefighters' firefighting shifts, as compared to levels following physical exertion without fire-fighting. Skin As the wildfires in California spewed smoke and ash into the air over the course of winter and fall dermatologists were concerned about how this could affect the skin of people exposed to it. Maria Wei is a graduate student at the University of California, Irvine. She examines how extreme wildfire pollution affects the skin. Her research was published on April 22 2012 in Scientific Reports. Wei's research has shown that the temperature of a person's skin varies based on how long the body is exposed to flames. It takes upwards of two hours for the skin to reach its flash point—the temperature at which it starts to burn and turns ashy. It's crucial not to be near a fire pit or campfire and wear protective clothing if out during a hot or humid day. Forest fires will continue occur, despite the steps taken to stop fires from causing pollution. Wei believes that as the climate changes cause forests to burn more, the number of people suffering from wildfires will grow. That means more people will need to wear hats, long sleeves, and thick moisturizers. It's also worth knowing that the atopic dermatitis (itchy skin) that many people suffer from is often exacerbated by wildfire air pollution. The particles in smoke can clog pores and cause atopic skin to become worse. Another issue is the fact that atopic dermatitis can make people more sensitive to UV light, which can be aggravated by smoke from wildfires. This can result in people seeking out tanning salons and get tanned with less protection. A treatment with ice and fire can help reduce atopic skin symptoms of dermatitis however it is not advised for anyone who has an open wound or rash. Patients with active acne should avoid it as well, and if you're nursing or pregnant, it's recommended to avoid this treatment completely. The IS Clinical Fire & Ice Facial is offered at Novuskin Las Vegas' premier membership MedSpa is a results-driven, intensive facial that bridges the mild facelift and the peel, but without the need for time off. It's designed to resurface the skin, improve the appearance of rosacea, reduce acne scarring, reduce wrinkles, and promote cellular renewal. This is a great treatment to provide your skin with a radiant glow. Infections The human body is a complicated network of organs and tissues that work to protect us from infection. Infections are caused by microscopic organisms like viruses, bacteria, parasites and fungus that invade healthy cells and cause them to reproduce out of control. Your immune system could react by displaying symptoms of illness. The symptoms could be anything from a snoring nose to an upset stomach and can also include swelling of lymph glands or an skin rash. The symptoms you experience can be affected by the nature of the infection, its location, and even your temperature. Infections can be spread through a variety of methods but the most prevalent are transmitted from person to person through droplets that linger in the air after sneezing or coughing. Bacterial diseases like tuberculosis and strep throat meningococcal disease, and Legionnaires' disease are spread in this manner, as do certain viral infections such as the common cold and influenza. bioethanol fire place -related infections, like skin infections and sexually transmitted infections (STIs) like gonorrhea or chlamydia are transmitted by contact with infected tissue or mucous membranes as well as indirect contact with contaminated surfaces. Some bacterial infections are spread by insects, such as ticks, fleas, or mosquitoes. Some parasites and viruses are small enough to penetrate your bloodstream and infect your cells, which leads to serious illnesses like the common cold or AIDS. Fungi cause many skin conditions, like ringworm and athlete's foot. Other types affect the lungs or the nervous system, like the rabies virus. The BioFire PN Panel uses our revolutionary FilmArray technology to test for a complete list of pathogens that are involved in upper respiratory infections in sputum or bronchoalveolar lavage fluid samples. The kit includes a reagent bag that contains all the chemistry needed to perform reverse transcription, nested multiplex PCR and detection in a single machine. It's an easy-to-use solution to help clinicians syndromicly identify and treat patients suffering from a variety of respiratory symptoms. This test has been given an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high-complex laboratories.